[Federal Register Volume 73, Number 42 (Monday, March 3, 2008)]
[Notices]
[Pages 11408-11410]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: E8-4051]
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ENVIRONMENTAL PROTECTION AGENCY
[FRL-8536-2; Docket ID No. EPA-HQ-ORD-2008-0048]
Draft Toxicological Review of 2-Hexanone: In Support of the
Summary Information in the Integrated Risk Information System (IRIS)
AGENCY: Environmental Protection Agency (EPA).
ACTION: Notice of public comment period.
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SUMMARY: EPA is announcing the public review and comment period for the
external review draft document titled, ``Toxicological Review of 2-
Hexanone: In Support of Summary Information on the Integrated Risk
Information System (IRIS)'' (NCEA-S-2764). The EPA intends to consider
comments and recommendations from the public and an expert panel
meeting, which will be
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scheduled at a later date and announced in the Federal Register, when
EPA finalizes the draft document. The public comment period will
provide opportunities for all interested parties to comment on the
document. EPA intends to forward public comments, submitted in
accordance with this notice, to the external peer-review panel prior to
the workshop for their consideration.
EPA is releasing this draft document solely for the purpose of pre-
dissemination peer review under applicable information quality
guidelines. This document has not been formally disseminated by EPA. It
does not represent and should not be construed to represent any Agency
policy or determination.
The draft document is available via the Internet on NCEA's home
page under the Recent Additions and the Data and Publications menus at
http://www.epa.gov/ncea. When finalizing the draft document, EPA
intends to consider any public comments that EPA receives in accordance
with this notice.
DATES: The public comment period begins February 28, 2008, and ends
April 28, 2008. Technical comments should be in writing and must be
received by EPA by April 28, 2008. EPA intends to submit comments from
the public received by this date to the external peer-review panel.
ADDRESSES: The draft Toxicological Review of 2-Hexanone: In Support of
Summary Information on the Integrated Risk Information System (IRIS) is
available via the Internet on the National Center for Environmental
Assessment's (NCEA) home page under the Recent Additions and the Data
and Publications menus at http://www.epa.gov/ncea. A limited number of
paper copies are available from NCEA's Technical Information Staff;
telephone: 703-347-8561; facsimile: 703-347-8691. If you are requesting
a paper copy, please provide your name, mailing address, and the
document title.
Comments may be submitted electronically via http://www.regulations.gov, by mail, by facsimile, or by hand delivery/
courier. Please follow the detailed instructions as provided in the
SUPPLEMENTARY INFORMATION section of this notice.
FOR FURTHER INFORMATION CONTACT: For information on the public comment
period, contact the Office of Environmental Information Docket;
telephone: 202-566-1752; facsimile: 202-566-1753; or e-mail:
[email protected].
If you have questions about the draft document, contact Amanda
Persad, IRIS Staff, National Center for Environmental Assessment, 109
T.W. Alexander Dr., Research Triangle Park, NC, 27709; telephone: 919-
541-9781; facsimile: 919-541-1818; or e-mail: [email protected].
SUPPLEMENTARY INFORMATION:
I. Summary of Information About the Integrated Risk Information System
(IRIS)
IRIS is a database that contains potential adverse human health
effects information that may result from chronic (or lifetime) exposure
to specific chemical substances found in the environment. The database
(available on the Internet at http://www.epa.gov/iris) contains
qualitative and quantitative health effects information for more than
540 chemical substances that may be used to support the first two steps
(hazard identification and dose-response evaluation) of a risk
assessment process. When supported by available data, the database
provides oral reference doses (RfDs) and inhalation reference
concentrations (RfCs) for chronic health effects, and oral slope
factors and inhalation unit risks for carcinogenic effects. Combined
with specific exposure information, government and private entities can
use IRIS data to help characterize public health risks of chemical
substances in a site-specific situation and thereby support risk
management decisions designed to protect public health.
II. How To Submit Technical Comments to the Docket at http://www.regulations.gov
Submit your comments, identified by Docket ID No. EPA-HQ-ORD-2008-
0048 by one of the following methods:
http://www.regulations.gov: Follow the on-line
instructions for submitting comments.
E-mail: [email protected].
Fax: 202-566-1753.
Mail: Office of Environmental Information (OEI) Docket
(Mail Code: 2822T), U.S. Environmental Protection Agency, 1200
Pennsylvania Ave., NW., Washington, DC 20460. The phone number is 202-
566-1752.
Hand Delivery: The OEI Docket is located in the EPA
Headquarters Docket Center, EPA West Building, Room 3334, 1301
Constitution Ave., NW., Washington, DC. The EPA Docket Center Public
Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through
Friday, excluding legal holidays. The telephone number for the Public
Reading Room is 202-566-1744. Such deliveries are only accepted during
the docket's normal hours of operation, and special arrangements should
be made for deliveries of boxed information.
If you provide comments by e-mail or hand delivery, please submit
one unbound original with pages numbered consecutively, and three
copies of the comments. For attachments, provide an index, number pages
consecutively with the comments, and submit an unbound original and
three copies.
Instructions: Direct your comments to Docket ID No. EPA-HQ-ORD-
2008-0048. Please ensure that your comments are submitted within the
specified comment period. Comments received after the closing date will
be marked ``late,'' and may only be considered if time permits. It is
EPA's policy to include all comments it receives in the public docket
without change and to make the comments available online at http://www.regulations.gov, including any personal information provided,
unless a comment includes information claimed to be Confidential
Business Information (CBI) or other information whose disclosure is
restricted by statute. Do not submit information that you consider to
be CBI or otherwise protected through http://www.regulations.gov or e-
mail. The http://www.regulations.gov Web site is an ``anonymous
access'' system, which means EPA will not know your identity or contact
information unless you provide it in the body of your comment. If you
send an e-mail comment directly to EPA without going through http://www.regulations.gov, your e-mail address will be automatically captured
and included as part of the comment that is placed in the public docket
and made available on the Internet. If you submit an electronic
comment, EPA recommends that you include your name and other contact
information in the body of your comment and with any disk or CD-ROM you
submit. If EPA cannot read your comment due to technical difficulties
and cannot contact you for clarification, EPA may not be able to
consider your comment. Electronic files should avoid the use of special
characters, any form of encryption, and be free of any defects or
viruses. For additional information about EPA's public docket visit the
EPA Docket Center homepage at http://www.epa.gov/epahome/dockets.htm.
Docket: All documents in the docket are listed in the http://www.regulations.gov index. Although listed in the index, some
information is not publicly available, e.g., CBI or other information
whose disclosure is restricted by statute. Certain other material, such
as copyrighted material, will be publicly available only in hard copy.
Publicly available docket
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materials are available either electronically in http://www.regulations.gov or in hard copy at the OEI Docket in the EPA
Headquarters Docket Center.
Dated: February 21, 2008.
Rebecca Clark,
Deputy Director, National Center for Environmental Assessment.
[FR Doc. E8-4051 Filed 2-29-08; 8:45 am]
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