[Federal Register Volume 73, Number 79 (Wednesday, April 23, 2008)]
[Notices]
[Pages 21941-21942]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: E8-8797]
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ENVIRONMENTAL PROTECTION AGENCY
[FRL-8556-5; Docket ID No. EPA-HQ-ORD-2008-0048]
Draft Toxicological Review of 2-Hexanone: In Support of the
Summary Information in the Integrated Risk Information System (IRIS)
AGENCY: Environmental Protection Agency (EPA).
ACTION: Notice.
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SUMMARY: EPA is announcing that Versar, Inc., an EPA contractor for
external scientific peer review, will convene an independent panel of
experts and organize and conduct an external peer-review meeting to
review the external review draft document titled, ``Toxicological
Review of 2-Hexanone: In Support of Summary Information on the
Integrated Risk Information System (IRIS)'' (NCEA-S-2764). EPA
previously announced the 60-day public comment period (ending April 28,
2008) for the draft document in the Federal Register on March 4, 2008
(73 FR 11408). EPA will consider public comments and recommendations
from the expert panel meeting as EPA finalizes the draft document.
The public comment period and the external peer-review meeting are
separate processes that provide opportunities for all interested
parties to comment on the document. EPA intends to forward public
comments submitted in accordance with Federal Register (73 FR 11408) to
Versar, Inc., for consideration by the external peer-review panel prior
to the meeting.
EPA is releasing this draft document solely for the purpose of pre-
dissemination peer review under applicable information quality
guidelines. This document has not been formally disseminated by EPA. It
does not represent and should not be construed to represent any Agency
policy or determination.
Versar, Inc., invites the public to register to attend this meeting
as observers. In addition, Versar, Inc., invites the public to give
brief oral comments at the meeting regarding the draft document under
review. The draft document and EPA's peer-review charge are available
via the Internet on the National Center for Environmental Assessment's
(NCEA) home page under the Recent Additions and the Data and
Publications menus at http://www.epa.gov/ncea. When finalizing the
draft document, EPA intends to consider Versar's report of the comments
and recommendations from the external peer-review meeting and any
public comments that EPA receives in accordance with 73 FR 11408, March
4, 2008. Public comments that were submitted during the 60-day public
comment period ending April 28, 2008 may be observed at http://www.regulations.gov under Docket ID No. EPA-HQ-ORD-2008-0048.
DATES: The peer-review panel meeting will begin on May 22, 2008, at 9
a.m. and end at 5 p.m. Register by May 16, 2008, if you wish to provide
brief oral comments at the meeting.
ADDRESSES: The peer-review meeting will be held at the Courtyard by
Marriott Crystal City, 2899 Jefferson Davis Highway, Arlington, VA
22202. Versar, Inc., is organizing, convening, and conducting the peer-
review meeting. To attend the meeting, register by May 16, 2008, via
the Internet at http://epa.versar.com/2hexanone/.
The draft ``Toxicological Review of 2-Hexanone: In Support of
Summary Information on the Integrated Risk Information System (IRIS)''
is available via the Internet on the National Center for Environmental
Assessment's (NCEA) home page under the Recent Additions and the Data
and Publications menus at http://www.epa.gov/ncea. A limited number of
paper copies are available from the Information Management Staff, NCEA;
telephone: 703-347-8561; facsimile: 703-347-8691. If you are requesting
a paper copy, please provide your name, mailing address, and the
document title. Copies are not available from Versar, Inc.
FOR FURTHER INFORMATION CONTACT: For information on the peer review
meeting, contact Stephanie Sarraino, Versar, Inc.; telephone: 703-750-
3000 ext. 316; e-mail: [email protected].
If you have questions about the document, contact Amanda S. Persad,
IRIS Staff, National Center for Environmental Assessment (B-243-01),
U.S. EPA, Research Triangle Park, NC, 27711; telephone: 919-541-9781;
facsimile: 919-541-1818; e-mail: [email protected].
SUPPLEMENTARY INFORMATION:
I. Summary of Information About the Integrated Risk Information System
(IRIS)
IRIS is a database that contains potential adverse human health
effects information that may result from chronic (or lifetime) exposure
to specific chemical substances found in the environment. The database
(available on the Internet at http://www.epa.gov/iris) contains
qualitative and quantitative health effects information for more than
500 chemical substances that may be used to support the first two steps
(hazard identification and dose-
[[Page 21942]]
response evaluation) of a risk assessment process. When supported by
available data, the database provides oral reference doses (RfDs) and
inhalation reference concentrations (RfCs) for chronic health effects,
and oral slope factors and inhalation unit risks for carcinogenic
effects. Combined with specific exposure information, government and
private entities can use IRIS data to help characterize public health
risks of chemical substances in a site-specific situation and thereby
support risk management decisions designed to protect public health.
II. Meeting Information
Members of the public may attend the meeting as observers, and
there will be a limited time for oral comments from the public. Please
let Versar, Inc. know if you wish to make comments during the meeting
by registering on the Web site at http://epa.versar.com/2hexanone/ and
indicating your intent to make oral comments. Space is limited, and
reservations will be accepted on a first-come, first-served basis.
Dated: April 15, 2008.
Peter W. Preuss,
Director, National Center for Environmental Assessment.
[FR Doc. E8-8797 Filed 4-22-08; 8:45 am]
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